Osteoporosis is a disease that affects bone density, making bones more fragile and prone to fractures. The traditional treatment for osteoporosis involves the use of bisphosphonates, drugs that inhibit the activity of osteoclasts, the cells responsible for bone resorption. However, the use of bisphosphonates can cause side effects such as esophageal irritation, fevers, eye inflammation and jaw osteonecrosis.
The present invention consists of a powder made up of bisphosphonate particles coated in biocompatible polyester. This patent allows for the controlled release of bisphosphonates, which aims to improve the effectiveness of osteoporosis treatment and reduce side effects.
The composite powder is produced by a process of coating bisphosphonate particles with biocompatible polyester. The polyester forms a protective layer around the bisphosphonate particles, which prevents them from being degraded or released quickly.
Patent title:
Composite powder for the production of biomaterials applied to tissue regeneration
Deposit Number:
BR 10 2019 025929 9
Pontifical Catholic University of Rio de Janeiro – PUC-Rio
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